Koss's Cytology of the Urinary Tract with Histopathologic Correlations 1 Ed.

Koss, Leopold G. ; Hoda, Rana S.
Koss's Cytology of the Urinary Tract with Histopathologic Correlations
Especialidad: Patologia
ISBN: 9781461420552
Publicación: 2012
Idioma: Ingles

1 Introduction
1 (6)
Historical Note
1 (4)
Suggested Readings
5 (2)
2 Indication, Collection, and Laboratory Processing of Cytologic Samples
7 (10)
General
7 (1)
Methods of Specimen Collection
8 (2)
Voided Urine
8 (1)
Catheterized Urine
9 (1)
Direct Sampling techniques
9 (1)
Ileal Bladder Urine
10 (1)
Laboratory Processing of Urinary Specimens
10 (5)
Liquid-Based Processing Techniques
10 (1)
SurePath
10 (4)
ThinPrep
14 (1)
Residual LBP Specimen
15 (1)
Suggested Readings
15 (2)
3 The Cellular and Acellular Components of the Urinary Sediment
17 (20)
Normal Lower Urinary Tract
17 (1)
Anatomy
17 (1)
Normal Urothelium (Transitional Epithelium) and Its Cells
18 (10)
Histology and Ultrastructure
18 (1)
Ultrastructure of the Umbrella Cells
19 (2)
Variants of Normal Urothelium
21 (1)
Cells Derived from Normal Urothelium
21 (7)
Other Benign Cells
28 (3)
Squamous Cells
28 (3)
Blood Cells
31 (1)
Erythrocytes
31 (1)
Noncellular Components of Urinary Sediment
32 (3)
Crystals
32 (3)
Suggested Readings
35 (2)
4 The Cytologic Makeup of the Urinary Sediment According to the Collection Technique
37 (10)
Introduction
37 (1)
Cytologic Makeup of the Sediment of Normal Voided Urine
37 (3)
Cell Preservation in Voided Urine
40 (1)
Cytologic Makeup of Bladder Washings
40 (2)
Cytologic Makeup of Normal Retrograde Catheterization Specimens
42 (1)
Cytologic Makeup of Smears Obtained by Brushing
43 (1)
Cytologic Makeup of Ileal Bladder Urine
44 (1)
Suggested Readings
45 (2)
5 Cytologic Manifestations of Benign Disorders Affecting Cells of the Lower Urinary Tract
47 (26)
Inflammatory Disorders
47 (1)
Bacterial Agents
47 (7)
Pyelonephrirtis
48 (1)
Cystitis
48 (1)
Hunner's Ulcer (Interstitial Cystitis)
49 (1)
Inflammatory Pseudopolyp
49 (1)
Eosinophilic Cystitis (Eosinophilic Granuloma)
50 (1)
Follicular Cystitis
50 (1)
Papillary Hyperplasia
50 (1)
Cystitis Cystica and Cystitis Glandularis
51 (1)
Nephrogenic Metaplasia (Adenoma)
52 (1)
Actinomyces and Norcardia
53 (1)
Tuberculosis
53 (1)
Fungal Agents
54 (1)
Viral Infections
55 (6)
Human Polyomavirus (Decoy Cells)
55 (4)
Herpes Simplex Virus
59 (1)
Human Papillomavirus
60 (1)
Cytomegalovirus
60 (1)
Cellular Inclusions Not Due to Viral Agents
61 (1)
Nonspecific Cytoplasmic Eosinophilic Inclusions (Melamed-Wolinska Bodies)
61 (1)
Parasites
62 (1)
Trematodes: Schistosoma haematobium
62 (1)
Other Parasites
62 (1)
Lithiasis
63 (1)
Leukoplakia
63 (3)
Effect of Drugs
66 (2)
Intravesically Administered Drugs
66 (1)
Systemically Administered Drugs
66 (1)
Cyclophosphamide (Cytoxan, Endoxan)
66 (2)
Busulfan (Myleran)
68 (1)
Effects of Radiotherapy
68 (1)
Urinary Cytology in Bone Marrow Transplant Recipients
68 (1)
Monitoring of Renal Transplant Patients
68 (1)
Rare Benign Conditions
69 (1)
Malakoplakia
69 (1)
Benign Giant Cells in Multiple Myeloma
70 (1)
Suggested Readings
70 (3)
6 Tumors and Related Conditions of the Bladder and Lower Urinary Tract
73 (36)
Non-neoplastic Changes
73 (3)
Urothelial Hyperplasia
73 (1)
Inverted Papilloma
74 (2)
Tumors
76 (1)
Epidemiology
76 (1)
Histologic Classification of Tumors of the Bladder, Renal Pelves, and Ureters
76 (2)
Two Pathways of Bladder Tumors
77 (1)
Low-Grade Papillary Urothelial Tumors with no/Minimal Nuclear Atypia
78 (1)
Low-Grade Papillary Urothelial Carcinoma
78 (1)
Cytologic Recognition of Low-Grade Tumors in Urinary Sediment
79 (1)
High-Grade Urothelial Tumors
80 (5)
High-Grade Papillary Carcinoma
80 (2)
Nonpapillary Urothelial Tumors
82 (3)
Invasive Urothelial Carcinomas
85 (2)
Histologic Patterns
85 (1)
Grading
85 (2)
Staging
87 (1)
Flat Carcinoma In Situ
87 (4)
Clinical Presentation
88 (2)
Histology
90 (1)
Cytologic Recognition of High-Grade Urothelial Tumors in Urinary Sediment
91 (5)
Histologic Variants of Urothelial Carcinoma
96 (8)
Squamous (Keratinizing) Carcinoma
96 (1)
Adenocarcinoma and Its Variants
96 (3)
Small Cell (Oat Cell) Carcinomas
99 (1)
Metastatic Tumors
100 (1)
Carcinoma and Precancerous States of the Uterine Cervix
100 (1)
Other Carcinomas of the Female Genital Tract
101 (1)
Prostatic Carcinoma
102 (1)
Carcinomas of Colon and Rectum
102 (1)
Carcinoma of Renal Cell Origin
102 (1)
Metastatic Carcinomas from Distant Sites
103 (1)
Other Metastatic Tumors
103 (1)
Cytologic Monitoring of Patients Treated for Tumors of Lower Urinary Tract
104 (1)
Reporting of Cytologic Findings
105 (1)
Suggested Readings
106 (3)
7 Urine-Based Assays Complementing Cytologic Examination in the Detection of Urothelial Neoplasm
109 (14)
Introduction
109 (1)
US FDA-Approved Markers
109 (4)
Bladder Tumor Antigen (BTA)
109 (1)
Nuclear Matrix Protein 22 (NMP22)
110 (1)
Fibrin-Fibrinogen Degradation Product (FDP)
111 (1)
ImmunoCyt
111 (1)
UroVysion
112 (1)
Potential Markers in Earlier Phases of Clinical Development
113 (4)
Bladder Cancer Antigen-4 (BLCA-4)
113 (1)
Survivin
114 (1)
UBC Tests
114 (1)
CYFRA 21-1
114 (1)
Hyaluronic Acid (HA)-Hyaluronidase (HAase)
115 (1)
Telomerase
115 (1)
Quanticyt
115 (1)
Fibroblast Growth Factor Receptor 3 (FGFR3)
116 (1)
Mucin 7 (MUC7)
116 (1)
VEGF
116 (1)
Markers Detected by Immunocytochemistry
117 (2)
CKs
117 (1)
p53
117 (1)
Ki-67
118 (1)
p16
118 (1)
Epidermal Growth Factor Receptor (EGFR)
118 (1)
E-Cadherin
118 (1)
Comparison Between Urine Cytology and FDA-Approved Markers
119 (1)
Conclusion
120 (1)
References
120 (3)
Index 123


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